Tuesday, December 11, 2012

New Antidepressant Acts Very Rapidly and is Long Lasting



http://www.sciencedaily.com/releases/2012/12/121207094604.htm

In lecture we’ve discussed various antidepressants and the corresponding neurotransmitters they act on. Recently, researchers have developed a new antidepressant that acts much faster and exhibits a prolonged therapeutic effect by targeting brain receptors responsible for learning and memory. I found this article exceedingly interesting as it exemplifies the interconnectedness of the brain, as well as two topics we’ve focused on in class.

The article states that this drug has proven helpful for individuals who did not have success with other traditional antidepressants and that they experienced symptom relief within hours. Further, participants are said to have reacted very positively and continued to display these beneficial effects for up to a week with a single dosage. It works by modulating the NMDA receptors in the brain, which we discussed is a process involved in long-term potentiation. Researchers assert that the side effects are mild to moderate and may be psychological since they seem to be similar to those observed in patients taking a placebo.

What’s even more surprising, and exciting, is that the article claims that the drug may alleviate other mental and neurological conditions including schizophrenia, bipolar disorder, anxiety, and Alzheimer’s disease.

Rightfully so, the article cautions that these findings require much research before they are sufficiently substantiated. Do you think that this drug is revolutionary or is it perhaps too good to be true? And if it does prove to be as effective and benign as the article suggests, how widely available should this drug be?

1 comment:

  1. As someone who has suffered from depression before, if what they are saying about this drug is true, this could be groundbreaking. This drug could potentially save thousands of lives because of its fast-acting qualities. Instead of waiting 6-8 weeks for antidepressants to work, someone who is suicidal only has to wait a matter of days. For sufferers with Alzheimer's and Schizophrenia, two diseases that currently have no cures, it would be life-changing.

    Due to the fact that this drug is still in the beginning stages of development and testing, I think it would be wise to not let one get their hopes up. It is possible that there are still undiscovered side effects that may outweigh the benefits.

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