Monday, November 5, 2012

Hydrogen bonds in Amyloid-beta peptide

http://www.sciencedaily.com/releases/2012/11/121105081451.htm

Researchers recently discovered that the cause of Alzheimer's may be Amyloid-beta peptide, not the amyloid plaques found in the brain of Alzheimer's patients.  This article discusses recent findings in the research of Amyloid-beta peptide.  Until now the structure of Amyloid-beta in its most dangerous form was not known but recently researchers at Lulea University of Technology and Warwick University have been able to use NMR spectroscopy to study the its hydrogen bonds.  Hydrogen bonds are essential to the structure and function of molecules.  Being able to identify the correct hydrogen bonds could lead to a treatment that blocks Alzheimer's instead of just attempting to alleviate symptoms.
 
While a cure is not imminent, this research does make an important step in the correct direction and could potentially help the millions of people currently struggling with Alzheimer's disease.  Researchers at Lulea University are already collaborating with other researchers to work towards fully characterizing the oligomers they believe are responsible for Alzheimer's disease. I believe that this research is important because being able to stop the progression of Alzheimer's instead of just treating the symptoms would change of the lives of millions of people around the world.

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